منابع مشابه
Text S 1 ( Analog regulation of metabolic demand )
The strength of graph theory is that it can represent a complex system in a unified formal language of nodes and links. Examples of graph-theoretical analyses of metabolic systems are [1] and [2]. Essentially, the pattern of zero and non-zero entries of the stoichiometric matrix defines a graph representation of the metabolic system. The level of information conveyed by looking at metabolism fr...
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15 صفحه اولGlial laminar cortical architecture matches metabolic demand.
The link between increased neural activity and cerebral blood flow is well established (Roy and Sherrington, 1890); yet, the mechanism by which blood flow is matched to neuronal activity both spatially and temporally is unclear. Based on their morphology, gray matter (protoplasmic) astrocytes are ideally situated to translate regional synaptic activity to hyperemia (increased flow) as they exte...
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Efforts to regionalize cardiac services can increase access costs for patients. This study quantifies this trade off by estimating the effects of changes in the regulation of hospital services on treatments and outcomes. A demand model for surgery services is specified in which heart attack victims form expectations of the need for and productivity of surgery in their choice of hospital and tre...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2011
ISSN: 1752-0509
DOI: 10.1186/1752-0509-5-40